Oh Oh Ohhhhh GLP-1!!!

Can you talk a bit about how it affected your relationship with food? Was it the nausea that kept you away from eating... making it easier to change your lifestyle/eating plan etc.? I'm just trying to figure out what I am in for vs. the whole placebo effect and the normal effects of writing down everything that goes into my mouth. Also, has changing the dose caused you to go right back to earlier patterns - or does some of it stick?
Man, that's tough, because there is a chicken and a egg thing there, yeah when I was nauseous obviously I did not each much, and I did learn that fried foods/rich foods generally lead to more nausea, but there was also some "good" foods that just seemed to give me some trouble like Tuna, idk why but it would always give me reflux with "tuna burps". And I love Tuna, but I don't really like tasting it 6 hrs later - I've always had bad acid reflux, though, but the zepbound can bring out the worst in it. That said, even on the very lowest dose before I ever had any side effects, I noticed a huge difference in "food noise" and just generally not being hungry all the time, forgetting to eat at times or going longer between meals, eating way smaller meals and feeling fulfilled and satisfied by them. I found myself naturally making healthier choices quite often just because when you're not as hungry and food loses it's power over you, it becomes so much easier. I have lots of skinny friends that just eat crap food but they eat less of it, and they don't think about food all the time. And in my head now I'm like, "ohhhhh, so THIS is what it must be like to be them...". I do eat better, but I still eat crap food sometimes, but I just eat small portions and have better control. Changing dose has not substantially affected me in a noticable way yet, but the last time I went down on dose, I did stop losing so... Something was going on, somewhere.
I imagine the effects are honestly highly indivualistic, so my experience may be entirely different from yours.
 
Thanks. I'm just trying to collect as much anecdotal data as I can before I dive in.

We all literally have the worst possible job for a healthy relationship with food. Heck, today I was texting back and forth with a friend who was on a delayed flight in the PR talking about how he was "lucky" to get Popeye's chicken fingers because they close at 1730 local - then he was delayed till a 2230 arrival at his destination when everything was closed. (especially after the drive to the hotel and such) Normally, I would have carried something in my bag for those kinds of situations - but I also would be eating too much after I arrive - right before I would go to bed. None of that is ideal.

Anyhoo, no point to that story from tonight except that I'm hoping that I'll be able to manage the stress of eating on the road a little better this time around while on the journey.
 
Second day after titrating up to 5mg and, so far, zero side effects.
Yeah, for most people if they do exist, they’re minor, and they don’t start til the higher doses. It sucks I'm one that’s affected but hey I’m still down nearly 80 lbs even if I have to just switch to a maintenance dose for now. Do you have the shotsy app? It’s helpful for visualizing how much is actually in your system. Because of the super long half life of these drugs, you still have about half of last week’s dose left in your system by the time you do the new dose. So like even tho I’m taking 7.5mg I have about 10mg in my system right now. Strangely I feel like I get the most issues 3 days after a shot, whereas for many people it seems to be the day after.
 

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Actually I did have some Saturday morning.

We were out with the neighbors and had a late night pizza/wings. Woke up at 0600 (I’m never up before 1000 most days at home) feeling like I had eaten two whole pizzas and six dozen buffalo wings and bloated AF. Back to bed at 1000, slept in until 1400 and finally felt normal about 1600. Ate a little protein and that was about it. Totally fine today. Fairly minor so far.
 
My experience on day 2 is… different. Maybe the placebo effect? (Placebos work when you know they are placebos…) I already think I feel the appetite decrease.

Day two is when you're at "peak". If you're running an app like "Shotsy" or "MeAgain", it'll show something like this:

Screenshot 2025-11-02 at 20.03.30.png


The 2.2mg day is the residual from my previous shots and the previous weeks GLP-1 level. That day I TOOK DA JABZZZ (sorry, crazy folks) then the next day you can see how the shot spiked my concentration levels.

My appetite on day two of my first shot in September affected my appetite off the bat. I felt the same, just felt fuller quicker and stayed feeling satisfied most of the day and the 'heft' of food I ate dove sharply. Hell, I had two cocktails on Halloween and that's pretty much the most I've drank for months in one sitting.

I heavily suggest "Shotsy" and an electronic scale to measure your progress for you and your doctor.
 
Day two is when you're at "peak". If you're running an app like "Shotsy" or "MeAgain", it'll show something like this:

The 2.2mg day is the residual from my previous shots and the previous weeks GLP-1 level. That day I TOOK DA JABZZZ (sorry, crazy folks) then the next day you can see how the shot spiked my concentration levels.

My appetite on day two of my first shot in September affected my appetite off the bat. I felt the same, just felt fuller quicker and stayed feeling satisfied most of the day and the 'heft' of food I ate dove sharply. Hell, I had two cocktails on Halloween and that's pretty much the most I've drank for months in one sitting.

I heavily suggest "Shotsy" and an electronic scale to measure your progress for you and your doctor.

I got the electronic scale - an awesome Withings one that I've had for more than a few years now. It rewards and shames me. I'll check out the apps - amazingly enough as soon as I started talking about this out loud all my socials started pushing ad's at me for shot tracker apps... whowouddaknown?

I'm checking off both of those boxes too - already feeling fuller even on this small dose right off the bat. (although my body knew I wasn't getting the same amount of/type of calories - I was getting other withdraw symptoms - historically I know that this will go away after 2-3 weeks from other lifestyle change journeys) It's just not as hard - which is a weird thing to say also right off the bat. I'm not feeling the constant call of Audrey II in my head... it's weird. I started keeping a journal to try to describe it to myself. I just wish my doc started me off on a higher dose for later in the week when the levels in my system drop off a bit.

Like last night - late. Normally I would have eaten way too much before bed. A small 80 cal pack of "probiotic yogurt fruit leather" things and some space strawberries made me feel totally "full."
 
I got the electronic scale - an awesome Withings one that I've had for more than a few years now. It rewards and shames me. I'll check out the apps - amazingly enough as soon as I started talking about this out loud all my socials started pushing ad's at me for shot tracker apps... whowouddaknown?

I'm checking off both of those boxes too - already feeling fuller even on this small dose right off the bat. (although my body knew I wasn't getting the same amount of/type of calories - I was getting other withdraw symptoms - historically I know that this will go away after 2-3 weeks from other lifestyle change journeys) It's just not as hard - which is a weird thing to say also right off the bat. I'm not feeling the constant call of Audrey II in my head... it's weird. I started keeping a journal to try to describe it to myself. I just wish my doc started me off on a higher dose for later in the week when the levels in my system drop off a bit.

Like last night - late. Normally I would have eaten way too much before bed. A small 80 cal pack of "probiotic yogurt fruit leather" things and some space strawberries made me feel totally "full."

It’s hit and miss sometimes.

I had a bowl of tortilla soup for dinner. Felt like I ate thanksgiving dinner but now that I’m up late doing some WFH stuff, I can kind of use a little snack but I’m way too lazy and it turned out I was just thirsty for some fizzy water.
 
And that sandwich was Top Five sandwiches too, so good, so I hated eating only about half of it. And the beer was delicious but my brain was happy with about 3/4’s of it over the span of what, four hours?

A month ago I would have eaten the whole thing and probably be drunk in your backyard after drinking all day, wondering who will deliver at midnight.
GLP meds slow down stomach emptying, keeping you feeling fuller longer. So that you don't eat as much.
 
My wife just started GLP-1 treatments and joked that I should do it with her. OF COURSE I thought the FAA would never allow that, and my AME would tell me to stop whining and get to crossfitting you fat-ass. Then I come here, and I am shocked at the reports of success and approval of the FAA. I truly value this community and its honesty.

This has influenced me to start the ball rolling and jump on the GLP-1 train to "better living through chemistry". I have always told my wife that I am not scared of checkrides anymore, I'm only scared of the bi-annual flight physical that could end my career. I was 170-180 when I was in my early 20's, the airlines made me 190-200, and now from being a parent and life hitting me hard in my late 40's im at 235. BTW im 5'8" so yea, I'm a fat bastard. Short-round. I can suck it in for posed photographs, but catch me in a side view or a candid shot and I look like the Stay Puft marshmallow man. I have found my belly has made life hard, and not being able to see what belt loop I am at when Im putting pants on scares me for the future. My mom was overweight, and my brother is overweight. I used to be super active, but being a chubby bunny really does negative wonders for motivation and frustration when it comes to sweating off the pounds.

So tomorrow I call my AME to discuss the paperwork trail and documents to acquire. Then call my regular-ass doctor to get that paperwork rolling, my last A1C reading was in the normal range, but more than 90 days ago. After that just follow the steps, I have two weeks off coming up at the end of December for observation, and then PROFIT

I will slap some questions for all yalls to ponder whomever has done THE SHOT
 
My wife just started GLP-1 treatments and joked that I should do it with her. OF COURSE I thought the FAA would never allow that, and my AME would tell me to stop whining and get to crossfitting you fat-ass. Then I come here, and I am shocked at the reports of success and approval of the FAA. I truly value this community and its honesty.

This has influenced me to start the ball rolling and jump on the GLP-1 train to "better living through chemistry". I have always told my wife that I am not scared of checkrides anymore, I'm only scared of the bi-annual flight physical that could end my career. I was 170-180 when I was in my early 20's, the airlines made me 190-200, and now from being a parent and life hitting me hard in my late 40's im at 235. BTW im 5'8" so yea, I'm a fat bastard. Short-round. I can suck it in for posed photographs, but catch me in a side view or a candid shot and I look like the Stay Puft marshmallow man. I have found my belly has made life hard, and not being able to see what belt loop I am at when Im putting pants on scares me for the future. My mom was overweight, and my brother is overweight. I used to be super active, but being a chubby bunny really does negative wonders for motivation and frustration when it comes to sweating off the pounds.

So tomorrow I call my AME to discuss the paperwork trail and documents to acquire. Then call my regular-ass doctor to get that paperwork rolling, my last A1C reading was in the normal range, but more than 90 days ago. After that just follow the steps, I have two weeks off coming up at the end of December for observation, and then PROFIT

I will slap some questions for all yalls to ponder whomever has done THE SHOT
I was 245-250 lbs. back in 2020. 215 now. You can do it!
 
My wife just started GLP-1 treatments and joked that I should do it with her. OF COURSE I thought the FAA would never allow that, and my AME would tell me to stop whining and get to crossfitting you fat-ass. Then I come here, and I am shocked at the reports of success and approval of the FAA. I truly value this community and its honesty.

This has influenced me to start the ball rolling and jump on the GLP-1 train to "better living through chemistry". I have always told my wife that I am not scared of checkrides anymore, I'm only scared of the bi-annual flight physical that could end my career. I was 170-180 when I was in my early 20's, the airlines made me 190-200, and now from being a parent and life hitting me hard in my late 40's im at 235. BTW im 5'8" so yea, I'm a fat bastard. Short-round. I can suck it in for posed photographs, but catch me in a side view or a candid shot and I look like the Stay Puft marshmallow man. I have found my belly has made life hard, and not being able to see what belt loop I am at when Im putting pants on scares me for the future. My mom was overweight, and my brother is overweight. I used to be super active, but being a chubby bunny really does negative wonders for motivation and frustration when it comes to sweating off the pounds.

So tomorrow I call my AME to discuss the paperwork trail and documents to acquire. Then call my regular-ass doctor to get that paperwork rolling, my last A1C reading was in the normal range, but more than 90 days ago. After that just follow the steps, I have two weeks off coming up at the end of December for observation, and then PROFIT

I will slap some questions for all yalls to ponder whomever has done THE SHOT

Welcome to the club!

I peaked about 228 in August and I'm barely over 200 now, but I'm still exercising and some limited strength training.

It's honestly been effortless and I don't feel like I've cheated myself at all. You can still eat what you want, you just feel satisfied quicker.

5'9 so I was a thicc boi.
 
Welcome to the club!

I peaked about 228 in August and I'm barely over 200 now, but I'm still exercising and some limited strength training.

It's honestly been effortless and I don't feel like I've cheated myself at all. You can still eat what you want, you just feel satisfied quicker.

5'9 so I was a thicc boi.

Thicc boi club! 20-30lbs in a few months is lifechanging! Congrats to everyone who has had a positive impact with this, and thanks for sharing! I would never have considered this if I hadn't come across this thread. I know this isnt a miracle drug, Im not trying to look like the kardashians, I just want to get back to who I was, and then stay there.

I'm built like a bulldog but snore like a hippo. Hoping this will help me sleep better, be less uncomfortable, and get back to who I was not long ago. The biggest hope is that this helps my motivation to get back on a bike and into the gym. Motivation to work out as a thicc boi, seeing yourself in the mirror sweaty and x-large with very little change in weight or body shape is truly demoralizing. I give mad props to the folks at the gym every day who are on the hefty side, making a change for themselves. The willpower needed to overcome your food demons is massive. I have tried the calorie counting, food prep, macros, and healthy shopping. But, when its 3pm and the food noise kicks in louder than an AC/DC concert and theres a box of Extra Toasty Cheez-its in front of you, the devil always wins. I like the idea of feeling full faster. I will sometimes eat like a dog until the stomach hurts, then I feel like a manatee. Put a pizza in front of me and I will just keep eating. It feels good to eat when you dont feel full. Until youre full...

Honestly the only stress right now is getting in to see my AME, and making sure it all falls in place so I can get started with the two week observation period at the end of December when I wont be working. I would prefer not to ask the Chief Pilot for time off to try some drugs instead of sweating to the oldies.

On that note, did this consultation/ppwk with your AME require a new medical? Or was it just a consultation? I had my last medical in Sept.

I also do that long-haul Europe stuff, has this made any impact on your body, mood, sleep, etc?

I like coffee, does coffee/caffeine consumption get affected by this?

And the $25,000 question, did the weight loss happen so fast that you were left with flappy skin?
 
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How long did the process with your GP and AME take before you were drugs in hand, ready to go? I know full well that the FAA is not expeditious.
 
The plot thickens....

Anyone have issues with receiving their special issuance medical after they have started GLP-1? I was told that by going on weight loss medications I will now have a SI medical, and sounds like that costs extra every 6 months. I think it will be worth the extra cost of a SI, but does it add any extra time or delays to getting your medical?
 
The plot thickens....

Anyone have issues with receiving their special issuance medical after they have started GLP-1? I was told that by going on weight loss medications I will now have a SI medical, and sounds like that costs extra every 6 months. I think it will be worth the extra cost of a SI, but does it add any extra time or delays to getting your medical?
You need a new AME. GLP-1 do not require a special issuance
 
Thicc boi club! 20-30lbs in a few months is lifechanging! Congrats to everyone who has had a positive impact with this, and thanks for sharing! I would never have considered this if I hadn't come across this thread. I know this isnt a miracle drug, Im not trying to look like the kardashians, I just want to get back to who I was, and then stay there.

I'm built like a bulldog but snore like a hippo. Hoping this will help me sleep better, be less uncomfortable, and get back to who I was not long ago.

I haven't woken up with a sore throat from snoring for six weeks so that's improved off the bat. I also wake up feeling like a million bucks, every day. But that's probably a combination of weight loss and vastly reduced alcohol consumption because I just don't desire it on the same level that I did. It tastes great but it doesn't trigger my pleasure receptors. It's a lot like having a coke. Half a glass is fine and then I'm tired of it compared to cracking a beer and immediately looking forward to the next because I feel like the king of the world.

The biggest hope is that this helps my motivation to get back on a bike and into the gym.

For me, yes. I wanted the GLP to give my body a 'reset' and I see results much faster. Plus Ive always enjoyed working out though.
But, when it's 3pm and the food noise kicks in louder than an AC/DC concert and theres a box of Extra Toasty Cheez-it's in front of you, the devil always wins. I like the idea of feeling full faster. I will sometimes eat like a dog until the stomach hurts, then I feel like a manatee. Put a pizza in front of me and I will just keep eating. It feels good to eat when you dont feel full. Until youre full...

My food noise is basically zero. But when I drank, I got snacky. Already digging in the fridge, might as well refresh that beer.

I made Posole Roja last weekend that's been in the fridge for almost a week, we still have pizza from last Friday and I basically have a month's supply of banana bread because they go old so quickly and a very small square and a espresso is like a satisfying indulgence but you do not psychologically feel like you're dieting because you're not. You just don't have the craving to eat in between meals and you feel satisfied faster.

Here's an example, I was out with friends for a "lazy lunch" a few weeks ago and I'm a motor-mouth during dinner. I got a tremendously delicious Pastrami sandwich and a beer, had a couple bites and told a story that went on for a little too long and realized that wasn't hungry anymore, felt full, and my beer had gotten warm. Not needing to wolf-down food to feed the beast gives you time to enjoy it and your body sends the "Bruv, we good, there's no place for this to go" far far earlier.

The key is that you can eat what you want, you just feel satisfied or naturally disinterested quicker.
On that note, did this consultation/ppwk with your AME require a new medical? Or was it just a consultation? I had my last medical in Sept.

Just a basic CACI form. I have the paperwork for the GLP but haven't had a medical since, but it's almost like the same form for my TRT/testosterone replacement therapy.

I also do that long-haul Europe stuff, has this made any impact on your body, mood, sleep, etc?

For me? Less fatigue, sleep better, better mood, only side effects are my usual "1600 and see a man about buying a horse" has become about 1900 when I'm at home.

I like coffee, does coffee/caffeine consumption get affected by this?

Coffee because I enjoy a cup with breakfast, but never because I need it to get started. Minimal/no desire for a cup in the middle of the office day on campus where I used to CHUG coffee to stay alert during the parade of never-ending "Dammit man, this could have been an email" meetings.


And the $25,000 question, did the weight loss happen so fast that you were left with flappy skin?

Nope! Work out, stay hydrated, stay on top of it. I'm petty and vain so I'm keeping an eyeball on that as well. :)

Tips: Get a blood glucose monitor and check it when you wake up and after a big meal, a Withings scale and a connected blood pressure monitor plus one of the apps like Shotsy or MeAgain. That way you can self-monitor your body changes with comparative charts and numerical data.

Like I had a heavy cardio week last week because it actually feels good to Peloton and brisk incline walk on the treadmill instead of watching YouTube on the couch and I had an above average weight loss that week so I scaled back this week and focused on weight training and less cardio.

Blood glucose rarely over 110 after even a relatively heavy meal, fasting is in the 70's, blood pressure is ridiculously awesome, I've gone down some sizes and even my uniform needs to be retailored but I'll wait until I'm at my target BMI and use the lifestyle changes to hopefully maintain that.

My only side affect has been how cold the pen feels against my belly before I push the button and almost like a "Bro DO YOU CROSSFIT" level of enthusiasm about the program. Seriously. But YMMV.
 
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