Thanks fellas, this is what I was afraid of. If flying planes was along a 9-5 schedule, it would work with a reserve commitment. Seems like airlines and reserves mix like oil and water.
No one here would say don't do it, quite the contrary. I'm thankful every day for Tricare Reserve Select, as my airlines health insurance is a joke. The benefits from being in the Reserve/Guard far outweigh the convenience of getting out completely. There are many guys that make it work out, just realize it is going to take more effort on your part.
I'm saying is that you need to more cognizant of how your life is arranged, organized, how you spend time and where you live, than the average airline guy, because time wasted commuting is a larger deal when you have something else that you need to be doing.
My own personal example. I am young, single and value having my weekends off as that is when my friends are off and that is when there are the most opportunities to socialize/have fun/blow steam off, which is important to me because being an airline pilot at a large regional is a decently isolating life. Of course due to the guard I am already down one weekend a month just for UTA. So now that I am senior enough to hold weekends off at the airline I would bid to fly M to Thur or Tues to Fri. If I had to do something for the military during the week I would schedule it for Mon, Tues or Thur, Fri, and simply deadhead to or from the hub to catch up with or get off a trip. This way I still ensure some quality time at home.
My last military chief pilot suggested I fly for the airline Fri to Mon and do guard Tues - Thurs, I declined that advice, it has taken me 3 years to get to upgrade at the airline instead of 1.5 years, because I do drop ~ 25 to 40 percent of my flying depending on the month, but I in no way regret choosing to try and have some semblance of normalcy in my life inasmuch as that I actually get to spend time with the girlfriend, friends and family vice texting them from the Hampton Inn Des Moines Airport (ie wherever) on a Saturday night wishing I was home, especially considering that 4 out of 22 months are spent overseas on deployment.
Life is too short to not attempt to balance, keep it sane and you'll be fine.