I'll add to the chorus of "it's not a big deal" either way.
The only change is a loss of "muscle memory" with respect to throttle and control positions, but you will get that when changing between aircraft any time (the throttle difference between a Skyhawk and a Cherokee, for example).
I think the same goes for when it's time to get that CFI (or be a right-seater in a heavy) and fly from the right side. A little different for a flight or so, then no big deal.
My preference is the left hand throttle, right hand stick config, but that's probably because that's how I have most of my flight time. I'm sure if I had most of my time in a yoke-left, throttle-right position then that is what I would prefer.