At ace a lot of times we weren't sure if the ground crew had given us reliable cargo weights, so not always no. Plus, if its icing on the ground, and you've gotten deiced and you're taxiing to go and its still icing, I'd always add a little bit to my speeds, can't hurt, and the runways are long anyhow. However, the engineering data might not necessarily have any margin of error built into it, you've got no way to know, so I usually don't trust it farther than what is logical, if you're getting a clearance to land on a 2000' runway in a 737 there's no point in pushing the envelope, wait five minutes and go to a better runway, it just seems to me that by trying to be efficient they costed the company millions and killed a little kid. You can "get er done," with out being a dumbass, just because the computer says its alright doesn't mean its prudent.