Next month is the 20th year since my first flight lesson. I sit here at my 2nd Part 121 job, but it was never a goal.
If you had asked 16-year old me if I would ever be an airline pilot, "No way". I did everything I could to prepare myself for other types of flying than airline flying. I was learning all about the corporate world and the path to get to there.
Then I got kicked out to the real world. It was an odd time, because times were changing. The hiring crack was just happening in 121. CFI jobs, 135 gigs, corporate gigs wouldn't take a look at me. A crappy little 121 operation did give me a look though. When you're hungry and have no where to live, you take what you can get.
I went into that job with the idea to get enough total time to go find a good 135 PIC or corporate job. Well, 9/11 happened before I had left, and the industry was again in shambles.
Next thing I know, it's 9 years later, and it's time to move on. By this time, the friends I had were scattered to all corners flying airplanes for a living. Some had great connections and got onto majors. Most got furloughed. A couple went corporate, and were jumping job to job coming up the corporate ranks (one of which is a member of this site, and now works at a Large Simulator company).
I'd realized that I'd adapted my life to the "121 Lifestyle", I'd gotten married when I was doing this type of flying and had our first child. Maybe it was a transcendental moment or something, but I'd realized that my "normal" was that kind of life. We had balanced our lives around the 121 life, for better or worse, with all of its peculiarities.
Maybe I'm just rambling and the point I have in my grey matter didn't get across, so I'll just type it out: Flying professionally, so much is out of your hands. You really have to go with the shifting sands of the industry, and carve out the best career you can. You will sacrifice for the job, so I don't see a reason to have self-induced suffering. Find a job track that suits your needs as best you can. Is it a lower paying, more days off job? Is it a higher paying, fewer days off? Maybe you'll be one of the lucky ones that gets the space shuttle ride to the top tier job of your dreams. In any case, enjoy the journey. The road ends, but no one knows where or how.
As for adapting to one lifestyle or another, like many of us, I have seen those that try to form the job to their lifestyle fail miserably; where those that form their lifestyle to the schedules of the job, regardless of industry segment, seem very happy.
That being said, I'm mid-career here, and have no guarantees of my job being here in another 5 years. Even so, I don't think I'd give up moving metal for a living for a cube farm job.