I have an original Brightline and a new modular style Brightline. I had purchased my original a few years ago, then after the new style came out, my parents surprised me with one of those for Christmas last year.
They are both good bags, and if you get the modular version you can buy other modules to customize it for a particular trip. You can also detach sections during a trip to make your gear fit in smaller spaces etc. I sometimes just travel with part of the bag on out and back trips, and leave the section I keep hygiene or overnight gear in back home.
I liked the original bag a lot for cross country organization too when I was still training for my commercial cert too. Plenty of pockets for gear and charts, and I could put two headsets in the main compartment. But I like the new bag even more, because you can add those modules for clothing or bigger binders if you need to.
I haven't used the bags a lot, as until recently I was working mostly as a CFI with just a headset and a kneeboard. But the original bag has probably been on at least twenty trips, and it still looks brand new and seems pretty durable. I have only used the new bag twice, just because I didn't need to carry so much on the trips and already had the original bag packed for my normal short trips.
When I got the new bag last year, there was a minor manufacturing defect. A zipper pull was bent such that it would not stay attached to the metal part that does the zipping. I don't remember if I went to Brightline's website or if there was a return instruction packed with the bag, but I contacted the company and they sent two replacement zipper pulls back to me within a week from my discovering the problem. I don't think it even cost me a postage stamp.
So far, I really like the bags and haven't seen anything I like better. I get to the 121 world one day and have to drag a bag of flight binders and gear and a little rolling suitcase around big airport terminals, the Brightline bag probably won't fit on the rolling suitcase too well. So I will more than likely have to change bags. But if I am working 135 or 91, small FBOs and no big gear drags to do, or just personal flying, I would probably still use my Brightline bag.