Not really. While you certainly need to know your stuff to deal with various country's ATC requirements and how and when to use things like CPDLC and HF, it's really not that hard to take off, engage the autopilot, make some FMC entries, eat dinner, stare out the window, take a nap, stare out the window some more, set up an approach in the FMC, turn off the autopilot, land, taxi in, go through customs and then go to the hotel and take a nap.
Honestly, the guy doing 4 legs a day on a 737, in the weather all day, or the guy on the CRJ doing 6 legs a day in the same weather, but into uncontrolled airfields some of the time, is actually more hardcore.
Guys bid longhaul because it's more relaxed, pays better and gives them more days off (in general) or because their junk is small and they want to fly a big plane to compensate. Not because it's the top of anything.