Configuration is very important when obtaining best glide in a single engine airplane. If you look in the POH for the aircraft there will usually be a chart for glide distance/altitude in the performance section. It will list the configuration used to obtain the performance listed in the chart. In the Piper Arrow it list the following conditions: Gear Up, Flaps Up, 79 KIAS, Power off, 2750 lbs (Max Weight), No Wind, Prop Full Decrease.
Gear and Flaps are obvious sources of drag and both will reduce glide distance. The prop is another large source of drag. Since most singles cannot be feathered it is best to reduce rpm as much as possible to reduce drag. Weight will not affect total glide distance, but at less than max weight best glide speed will be lower than the 79 KIAS listed in the chart. Use the VSI to find the exact number. Wind will also change best glide speed. If you are going into the wind a faster speed will give the most distance over the ground.
The prop governors of many singles work the opposite of a multi-engine airplane. In most multi's oil pushes the prop to low pitch, high rpm. If oil pressure is lost the prop will feather. In a single the oil pushes the prop to high pitch, low rpm. If oil pressure is lost the prop will go to low pitch, high rpm. So if you loose oil pressure from an oil leak, etc. You will not be able to reduce the prop rpm. If the engine just quits and is windmilling it will develop sufficient oil pressure to reduce prop rpm.