Yes. The Form 8500-8 asks "Do you currently use any medication (prescription or nonprescription)?
The notice at the bottom of Form 8500-8 states: "Whoever in any matter within the jurisdiction of any department or agency of the United States knowingly and willingly falsifies, conceals or covers up by any trick, scheme, or device a material fact, or who makes a false, fictitious or fraudulent statements or representations, or entry, may be fined up to $250,000 or imprisoned not more than 5 years or both. (18 U.S. Code Secs. 1001; 3571)"