If your goal is the majors, then first off you're going to have to get 1500 hours and get some turbine time if not turbine PIC. The regional game changes so quick, no point worrying about who pays what now and is based where. Just worry about what commercial flying jobs you wouldn't hate until you get that 1500 hours, then worry about the next move. In the mean time, you're obviously concerned with the crappy pay. What else do you like to do other than fly? What are your hobbies? More importantly, what are your talents? Find a way to make money off something you're good at, like to do, and that you can have enough time to work on while flying. That's what I'm doing, and it's nice to just be concerned with the costs of flight training and not really care what I'll get paid when I get there. Also, be creative. Once you have your commercial certs, you have the legal ability to fly a freggin airplane and get paid to do it. There's a lot of people that would love to use an airplane for stuff other than hauling freight or people from point A to point B. Network.
I'll add, going back to how fast the regional game changes, I'll give you a quick example. I started working for Skywest as a gate agent in 2008. At the time, they flew for United, Delta, and Midwest with lots of out station crew bases on the West Coast(SMF, SBP, ect). By the time I left to be a ramp controller in very early 2013, most of the West Coast bases had closed, hubs became much larger domiciles, Midwest(and the MKE base) went bye bye, MKE flying restarted with AirTran flying(I'm sorry, I mean a "codeshare" with AirTran) for a hot minute, US Airways then American flying were added with new domiciles, and the UA/CO merger brought in an IAH base. Again, don't worry about the regional QOL, pay, and domiciles right now. It'll all change by the time you're ready to apply.