I took my checkride in one of those yesterday. The check airman said I flew a great ride, though he made me do my V1 cut twice. I think the first one was legal but sloppy on the directional control, and we had time to kill in the sim, so I got to do it again. The second time (with some prompting from my sim instructor who was in the left seat), I got more rudder in and it went better.
The profile was normal takeoff, FMC route mods, departure stall, a normal ILS, two non-precision approaches, V1 cut (engine failure on takeoff) and a single engine ILS, hand flown to minimums. The last one is the hardest cause you always have a crosswind and the weather is 2400 rvr. Thank gawd for flight directors. I don't know why something that seems so easy in a 172 is so hard in the jet....must be the difference is between 140 knot approaches (single engine) and 80 knots. Also, a 172 seems pretty stable compared to these big sims. They look cool and all but they are HARD to hand fly. Maybe it's just me but I'm always overcontrolling like crazy and making life harder than it needs to be. I think given another 10 sim rides, I'd feel better about it but the philosophy is to kick you out the door with the minimum time, as long as you meet the standard. More than that just costs the company extra money.
I remember from my 727 training 10 years ago that the real plane was much easier to fly than the sim...and a lot more fun cause it doesn't catch on fire as much....