There was a NOTAM like this hanging around at KCHS for awhile, and I called the tower to see if they had any further explanation. It was just a ramp construction thing where they wanted to avoid taking several unscheduled aircraft on a construction-limited ramp. I think the same thing may still be going on KOKC.
In this case, I'd probably take the CYA strategy and just file a takeoff alternate. It makes me wonder though -- if you don't file a takeoff alternate, is it assumed for planning purposes that if the need were to arise, the aircraft can and should return to the departure airport? Is that considered an implicit part of the flight plan, even if it is not listed explicitly as the preferred destination for a post-takeoff diversion? If you take that interpretation, then it defies the NOTAM's instructions. That's where I would probably not F with it, and tack on a T/O ALT that's reliable. Then again, I think most would agree that the NOTAM would instantly become moot if the need did arise, because that need would almost always entail some kind of emergency condition, as pljenkins explained.