Biggest thing is: DO NOT lift off before Vmc!
If you rotate early, it will lift off WELL before Vmc placing you in a very bad spot. Unlike virtually every twin trainer where Vmc is a theoretical value since it is below Vso anyway. This thing will show you a neat snaproll if you are below red line and you lose an engine.
Other than that, the PT-6 is virtually pilot proof, and the airframe is built like a tank (and handles like one too).