Sooner or later, it will happen. It's almost possible today, in limited circumstances. Airplanes do land themselves. Drones work. Derg could bike to work in a drone bunker outside Vegas!
The first question is: at what cost? In crashes, when things go beyond the automation's envelope. In lives, both in the aircraft and on the ground? When do humans step in as an incident starts? Will they have enough practice to know what to do (do they always now?) Will society accept the limitations and consequences? Will ERAU start a law school?
In a way, this reminds me of the head of the US Patent Office in (I believe) the 1890s, who seriously recommended that the patent office be shut down. Why? he was asked. 'Because everything that could be invented, already had been.' he replied.