Just did my ATP MEL in a Seminole last friday. Pretty straight forward. Had me go through each of the systems which is all fairly basic (engine, prop, gear, controls, electrical). Wanted to talk about anti/deicing equipment but there isn't any to speak of on our Seminole so not much to talk about. Talked about all the performance numbers ie. take off roll, accel-stop, landing roll, climb 2 engine and 1 engine, service ceilings etc. Also went over considerations for flying a light twin at high density altitudes. Really the oral was relatively easy. The flight portion wasn't hard but it was work load intensive. He had me file and IFR flight plan and we got a clearance and then asked for a diversion and a hold. Next we asked for a block of airspace and did steep turns, a couple stalls and unusual attitudes. Then shot a VOR approach to a circle to land then a single engine GPS with a single engine missed. Then did a DME arc for an ILS to straight in landing then 2 more GPS approaches and another ILS. After this, a full engine shutdown then normal landing and we were finished. Very straight forward with no real surprises. Just lots of instrument (spent 2.7 of a 2.9 flight under the hood). Like I said before workload was high but I fly ag planes and the most IFR flying I'd done in 2 years was maybe 2 hours of actual and about 2 hours of prep for the check.
Hope this helps and good luck!